Participation of the cannabinoid system and the NO/cGMP/KATP pathway in serotonin-induced peripheral antinociception

DD Aguiar, JA Petrocchi, GC da Silva, VS Lemos… - Neuroscience …, 2024 - Elsevier
… the paw of mice. Taken together, these data suggest that the … is related to the activation of
the nitric oxide/cyclic guanosine … intraperitoneal injection of 10 % ketamine (Cayman Chemical) …

Cannabidiol induces systemic analgesia through activation of the PI3Kγ/nNOS/NO/KATP signaling pathway in neuropathic mice. A KATP channel S-nitrosylation …

DL de Almeida, RCM Ferreira, FC Fonseca… - Nitric Oxide, 2024 - Elsevier
… In this procedure, animals were first anesthetized with a 10% ketamine hydrochloride … the
peripheral tissues and how that nitric oxide affects the CDB-mediated antinociception observed …

Nitric oxide and potassium channels but not opioid and cannabinoid receptors mediate tramadol-induced peripheral antinociception in rat model of paw pressure …

RR Soares-Santos, DP Machado… - Canadian Journal of …, 2023 - cdnsciencepub.com
… intraperitoneal injection of anesthetic (300 mg/kg ketamine … not activate peripheral opioid
receptors, we propose that it … of the nitric oxide-cyclic GMP pathway, Eur. J. Pharmacol. …

[HTML][HTML] Anti-allodynic effect induced by curcumin in neuropathic rat is mediated through the NO-cyclic-GMP-ATP sensitive K+ channels pathway

T Pastrana-Quintos, G Salgado-Moreno… - … medicine and therapies, 2020 - Springer
… that drugs which activate the NO-cGMP pathway seem to … Rats were anesthetized with a
mixture of Ketamine (45 mg/kg… the opening of K + channels induces anti-nociception [36, 40]. In …

Artemisia biennis Willd.: Anti-Nociceptive effects and possible mechanisms of action

M Zarei, D Ahmadimoghaddam… - Journal of …, 2021 - Elsevier
… Animals were anesthetized with ketamine (60 mg/kg), xylazine (6 mg/kg), and … on
ABAEO-induced peripheral antinociception during the early phase in Swiss mice formalin induced

[HTML][HTML] Narrative review: low-dose ketamine for Pain Management

A Riccardi, M Guarino, S Serra… - Journal of Clinical …, 2023 - mdpi.com
… by ketamine appears to disinhibit pyramidal neurons, activate … action of ketamine on sodium
channels at peripheral nerve … In rats, the lethal dose of ketamine is well above 40 mg/kg [45]…

[HTML][HTML] … /morphine crosstalk accounts for antinociception and hepatoprotection in hepatic fibrosis in rats: Distinct roles of opioid/cGMP and NO/KATP pathways

AF Bedair, A Wahid, NS El-Mezayen… - Biomedicine & …, 2023 - Elsevier
… as NO and cyclic guanosine monophosphate (cGMP) are also … by several drugs including
morphine, diclofenac, ketamine, … abrogate the antinociception indicated that GC is activated by …

The Relationship of Glutamate, Oxidative and Nitric Oxide Pathways in the Analgesic Effect of Growth Hormone in a Model of Peripheral Neuropathy

S Saffarpour, P Sadeghi Tehran… - … in a Model of Peripheral … - papers.ssrn.com
… fibers leads to NMDA receptor activation and calcium influx. … In short, the adult male rats
were anesthetized with ketamine (… Recent studies have identified the antinociceptive effect of …

The Involvement of Oxidative Stress and Glutamate and Nitric Oxide Pathways on the Analgesic Effect of Genotropin in a Model of Peripheral Neuropathy

S Saffarpour, P Sadeghi-Tehran, A Mehraz… - Available at SSRN … - papers.ssrn.com
… fibers leads to NMDA receptor activation and calcium influx. … been shown to induce
antinociceptive effects in inflammatory … In short, the adult male rats were anesthetized with …

Comparison of Ketamine Nebulisation with Ketamine Gargle in Attenuating Post Operative Sore Throat Following General Anaesthesia with Endotracheal Intubation

A Modak, E Rasheed, N Bhalerao… - Journal of …, 2021 - eprints.go4mailburst.com
ketamine in an experimental model with rats [15]. Furthermore, animal studies have
shown that peripherally given ketamine can activate the Larginine/Nitricketamine in antinociception/ …